Capping And Lamination

A cross section of a tablet without capping or.

Capping and lamination.

Tablet capping and lamination powder compaction is widely used to produce pharmaceutical tablets and is referred to as a tabletting process. Main reason for lamination is attributed to presence of bands cracks in tablet whereas presence of air in. Usually capping and lamination occur during or after tablet manufacturing and may therefore influence follow up processes such as the coating. In this context there is an urgent need for approaches to overcome the occurrences of capping and lamination.

Lamination is the term used for a split in the tablet anywhere but at the top. Moreover lamination is caused by either there being an. Lamination is also caused by the presence of a large amount of fines in the granulations. Causes and remedies of capping in tablet manufacturing.

Carl zeiss oberkochen germany was only used to illustrate the difference between capping and lamination. Removing some or all the fines through the 100 mesh screen will reduce the chances of lamination occurring by a higher percentage. Capping and lamination are classical industrial issues that can be challenging during the scale up of solid dosage forms. Lamination is separation that occurs at any other part of the tablet except the top or bottom.

Although the method is widely used there are still significant challenges with achieving a high quality compact. The capping or lamination indices were determined in triplicate whereby the total number of investigated tablets n t was 20 for each measurement. Tablet lamination is most common problems observed during compression of tablets it is often misconceived with capping problem firstly we need to understand lamination to rectify it as both capping and lamination have different reasons and different rectifications. Previous publications showed that changing the unloading conditions triaxial decompression loaded ejection made it possible to mitigate capping.

Lamination is essentially the same as capping and with similar causes. Capping and lamination are common defects that occur during tablet manufacturing. Capping happens when the upper or lower part of a tablet separates horizontally photo as the press ejects the tablet.